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Updated: May 18, 2026

08:31
Optimized Griess Reaction for UV-Vis and Naked-eye Determination of Anti-malarial Primaquine
Published on: October 11, 2019
Reinventing primaquine for endemic malaria
Expert Opinion on Emerging Drugs
|September 25, 2012
Summary
Primaquine is the only malaria drug for transmission and relapse but its dosing is unsafe for many. New, safer primaquine dosing strategies are needed, possibly using co-drug synergies.
Area of Science:
- Tropical medicine
- Pharmacology
- Parasitology
Background:
- Primaquine is the sole licensed therapy for malaria transmission and relapse, developed by the US Army.
- Current dosing strategies were designed for soldiers and not validated for broader populations.
- These strategies pose risks, particularly hemolytic toxicity in glucose-6-phosphate dehydrogenase deficient individuals.

