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Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

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Infection retardant coated inflatable penile prostheses decrease the incidence of infection: a systematic review and

Sree Harsha Mandava¹, Ege Can Serefoglu, Matthew T Freier

¹Department of Urology, Tulane University, New Orleans, Louisiana 70112, USA.

The Journal of Urology

|September 25, 2012

Summary

Infection retardant coated inflatable penile prostheses significantly reduce device infection rates compared to noncoated devices. This finding highlights the benefit of antibiotic-eluting coatings in preventing surgical implant infections.

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High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

Published on: November 5, 2016

Area of Science:

Urology
Infectious Disease
Biomaterials Science

Background:

Postoperative infections are a significant complication following inflatable penile prosthesis (IPP) implantation.
Reducing the incidence of surgical site infections (SSIs) is crucial for improving patient outcomes and device longevity.

Purpose of the Study:

To systematically compare the effectiveness of infection retardant coated IPPs versus noncoated devices in preventing postoperative infections.
To determine if implant coatings impact the rate of surgical implant infection.

Main Methods:

A systematic review of PubMed and Galileo databases was conducted to identify relevant case studies.
Postoperative infection incidence rates were compared between coated and noncoated IPPs.

Main Results:

Analysis included 14 case studies with 9,910 patients; 5,214 noncoated and 4,696 coated IPPs.
Infection rates were 2.32% for noncoated vs. 0.89% for coated IPPs (p <0.01).
Specific coated IPPs showed varying infection rates: minocycline/rifampin (0.63%), rifampin/gentamycin (0.55%), vancomycin/gentamycin (4.42%), and hydrophilic (1.11%).

Conclusions:

Coated IPPs offer a significant advantage in preventing postoperative device infections compared to noncoated devices.
Antibiotic-eluting coatings reduce device infection incidence by approximately 50%.
Future research should explore novel techniques, such as preventing bacterial adhesion, to further minimize infectious complications.