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Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens
Published on: February 14, 2011
A case of Histoplasma capsulatum endophthalmitis diagnosed in Italy
Anna Grancini1, Manuela Colosimo, Chiara Mapelli
1Fondazione IRCCS Cà-Granda Ospedale Maggiore Policlinico, Via F. Sforza 35, Milan, Italy. anna.grancini@libero.it
Abstract:
Histoplasma capsulatum var. capsulatum is a dimorphic fungus endemic in the eastern United States and most countries of Latin America. Sporadic cases of histoplasmosis have been reported in Europe, mainly in immigrants or people returning from highly endemic areas. We report a case of 64-year-old Italian man with endophthalmitis, an unusual presentation of H. capsulatum infection. The patient shows redness, blurred vision, localized pain in the right eye. H. capsulatum was cultured from a vitreous biopsy and yeast forms were seen at histology.
Insights
A rare case of endophthalmitis caused by Histoplasma capsulatum (H. capsulatum) infection was diagnosed in an Italian man. This fungal infection, typically found in endemic areas, presented unusually in the patient's eye.
Area of Science:
- Mycology
- Infectious Diseases
- Ophthalmology
Background:
- Histoplasma capsulatum var. capsulatum is a dimorphic fungus endemic to the eastern United States and Latin America.
- Sporadic cases of histoplasmosis occur in Europe, often in travelers or immigrants from endemic regions.
- Endophthalmitis is an uncommon manifestation of Histoplasma capsulatum infection.
