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Intermittent Cushing's disease with spontaneous remission
Clinical Endocrinology
|November 1, 1979
Summary
This study details a Cushing's syndrome patient with intermittent remission, revealing persistent hypothalamic pituitary axis dysfunction despite normal cortisol levels. This suggests a subtle, localized defect affecting adrenocorticotropic hormone (ACTH) regulation.
Area of Science:
- Endocrinology
- Neuroendocrinology
- Clinical Medicine
Background:
- Cushing's syndrome is characterized by excessive cortisol production, often due to adrenocorticotropic hormone (ACTH) over-secretion.
- Spontaneous remissions in Cushing's syndrome are rare, making prolonged study periods crucial for understanding disease dynamics.