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Published on: August 18, 2015
Takotsubo cardiomyopathy as a source of cardioembolic cerebral infarction
Sun Moon Kim1, Shamik Aikat, Alison Bailey
1Department of Internal Medicine, University of Kentucky, Lexington, Kentucky, USA.
Insights
Takotsubo cardiomyopathy, a stress-induced heart condition, can rarely lead to stroke. Prompt anticoagulation and echocardiography are crucial for managing this rare cardioembolic complication.
Area of Science:
- Cardiology
- Neurology
Background:
- Takotsubo cardiomyopathy (TTC) is a stress-induced heart condition often mimicking myocardial infarction.
- It typically affects postmenopausal women and is characterized by left ventricular dysfunction without obstructive coronary artery disease.
Observation:
- A rare case of TTC presented with intracardiac mural thrombus formation.
- This thrombus led to a cerebral infarction, a cardioembolic event.
Findings:
- The patient was successfully treated with anticoagulation therapy.
- Serial echocardiograms revealed resolution of the apical thrombus and recovery of cardiac function within 4 months.
Implications:
- This case highlights the potential for rare cardioembolic complications in TTC.
- It underscores the importance of serial echocardiographic monitoring and anticoagulation in managing TTC patients at risk for embolic events.
Abstract:
Takotsubo cardiomyopathy is a stress-related cardiomyopathy that mimics acute myocardial infarction. However, it is frequently without obstructive coronary artery disease and is mainly seen in postmenopausal women after an emotional or physiological event. In rare cases, it favours the formation of intracardiac mural thrombus and subsequent cardioembolic events. We report a rare case where a patient developed a cerebral infarction as a cardioembolic sequela of takotsubo cardiomyopathy following the death of her beloved dog. The patient was successfully managed with anticoagulation where a repeat echocardiogram 4 months later showed resolution of the apical thrombus along with recovery of systolic function and left ventricle regional wall abnormalities. This case serves to increase awareness about the rare cardioembolic complications of takotsubo cardiomyopathy and emphasise the need for serial echocardiographic examinations and anticoagulation.
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