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Updated: May 18, 2026

Methods for Experimental Manipulations after Optic Nerve Transection in the Mammalian CNS
Published on: May 12, 2011
Management options for visual pathway compression from optic gliomas
Anne-Caroline Bessero1, Clare Fraser, James Acheson
1Lysholm Department of Neuroradiology, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK.
Abstract:
Optic pathway gliomas (OPGs) manifest with neuro-ophthalmic symptoms and signs; however, presentation can vary as their location and growth patterns are highly variable. An exophytic expansion of an OPG within the intracranial cavity can cause compression on neurological structures, warranting intervention. However, management guidelines are limited and the treatment itself may also cause neuro-ophthalmic complications. Therefore, clinical decision-making must include input from a multidisciplinary team that includes ophthalmology, neurosurgery, radiation oncology and neuroradiology.
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