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Nanopore DNA Sequencing for Metagenomic Soil Analysis
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Nanopore DNA Sequencing for Metagenomic Soil Analysis

Published on: December 14, 2017

PEG-labeled nucleotides and nanopore detection for single molecule DNA sequencing by synthesis

Shiv Kumar1, Chuanjuan Tao, Minchen Chien

  • 1Center for Genome Technology & Biomolecular Engineering, Department of Chemical Engineering, Columbia University, New York, NY 10027, USA.

Scientific Reports
|September 25, 2012
PubMed
Summary

This study introduces a novel nanopore sequencing by synthesis (Nano-SBS) method. It accurately identifies DNA bases by detecting unique tag signatures as nucleotides are incorporated, enabling single-molecule DNA sequencing.

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