CDX2 highlights mucinous epithelium in hepatoblastoma with teratoid components

Originally only considered as a maker for intestinal differentiation, CDX2 was later found to be expressing in other tumors outside of gastrointestinal (GI) tract. We report an interesting phenomenon that CDX2 also highlighted the teratoid component in hepatoblastoma-its mucinous epithelium. It is speculated that CDX2 can be a good marker for mucinous differentiation with morphological intestinal characteristics in general.