Related Experiment Video
Updated: May 18, 2026
09:49
Routine Screening Method for Microparticles in Platelet Transfusions
Published on: January 31, 2018
A reporting guideline for clinical platelet transfusion studies from the BEST Collaborative
Erin Meyer1, Meghan Delaney, Yulia Lin
1Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA. emeyer5@emory.edu
Transfusion
|September 26, 2012
Summary
This study developed a reporting guideline for platelet (PLT) transfusion trials using the Delphi method. The final checklist improves the design, reporting, and critique of PLT transfusion studies.
Area of Science:
- Hematology
- Clinical Trials
Background:
- Systematic review revealed gaps in reporting platelet (PLT) transfusion trials.
- Inconsistent descriptions of trial design, variables, and outcomes were identified.
Purpose of the Study:
- To systematically develop a reporting guideline for PLT transfusion trials.
- To improve the design, reporting, and critique of clinical PLT studies.
Main Methods:
- Expert opinion and the Delphi method were used to develop a preliminary checklist.
- Three rounds of expert review and consensus-building refined the checklist items.
- A 7-point Likert scale guided item inclusion based on expert consensus.
Main Results:
- A preliminary 23-item checklist was refined and expanded to 30 items.
- The final checklist includes sections on methods, intervention, PLT-specific outcomes, results, and adverse events.
- An explanatory guide was added to enhance the reporting guideline.
Conclusions:
- The Delphi method successfully achieved expert consensus on reporting items for PLT transfusion trials.
- The developed checklist and guide will enhance the quality of PLT transfusion study reports.
- Authors and editors can utilize this guideline to improve scientific communication in the field.
