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Related Experiment Video

Updated: May 18, 2026

Directly Measuring Forces Within Reconstituted Active Microtubule Bundles

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Published on: May 10, 2022

Unifying model of driven polymer translocation.

T Ikonen¹, A Bhattacharya, T Ala-Nissila

¹Department of Applied Physics and COMP Center of Excellence, Aalto University School of Science, P.O. Box 11000, FI-00076 Aalto, Espoo, Finland.

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics

|September 26, 2012

Summary

This summary is machine-generated.

We developed a polymer translocation model incorporating tension propagation (TP) effects. Our findings reveal finite chain length impacts dynamics, explaining experimental variations and improving translocation theories.

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Area of Science:

Polymer physics
Statistical mechanics
Biophysics

Background:

Polymer translocation is crucial for biological processes.
Existing models often neglect nonequilibrium memory effects.
Understanding driven polymer dynamics is key.

Purpose of the Study:

To develop a Brownian dynamics model for driven polymer translocation.
To incorporate nonequilibrium memory effects via time-dependent friction.
To investigate the influence of finite chain length on translocation dynamics.

Main Methods:

Developed a finite chain length tension propagation (TP) formalism.
Incorporated TP as a time-dependent friction in a Brownian dynamics model.
Validated the model against molecular dynamics simulations.

Main Results:

The model accurately reproduces simulation data across various parameters.
Nonequilibrium TP along the cis side subchain dominates translocation dynamics.
Observed translocation dynamics differ significantly from asymptotic limits for typical chain lengths.

Conclusions:

Finite chain length effects are critical for accurate polymer translocation theories.
The developed model explains discrepancies in experimental scaling laws.
Explicit consideration of finite chain length is necessary for quantitative polymer translocation studies.