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Updated: May 18, 2026

High Throughput Single-cell and Multiple-cell Micro-encapsulation
Published on: June 15, 2012
Packings of monodisperse emulsions in flat microfluidic channels
Ohle Claussen1, Stephan Herminghaus, Martin Brinkmann
1Max-Planck Institute for Dynamics and Self-Organization, Bunsenstrasse 10, 37073 Göttingen, Germany.
Abstract:
In the lateral confinement of a flat microfluidic channel, monodisperse emulsion droplets spontaneously self-organize in a variety of topologically different packings. The explicit construction of mechanically equilibrated arrangements of effectively two-dimensional congruent droplet shapes reveals the existence of multiple mechanical equilibria depending on channel width W, droplet area A{d}, and volume fraction φ of the dispersed phase. The corresponding boundaries of local or global stability are summarized in a packing diagram for congruent droplet shapes in terms of the dimensionless channel width w=W/sqrt[A_{d}] and φ. In agreement with experimental results, an increasingly strong hysteresis of the transition between single-row and two-row packings is observed during changes of w above a threshold volume fraction of φ≃0.813.

