Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Planar Rigid-Body Motion01:22

Planar Rigid-Body Motion

Understanding the movement of a rigid body in planar motion involves recognizing that every particle within this body is traversing a path that maintains a consistent distance from a specific plane. This concept is fundamental in the study of physics and mechanical engineering, and it allows us to comprehend better how objects move in space.
Planar motion is typically divided into three distinct categories. The first is rectilinear translation, demonstrated by a subway train that moves along...
Relative Motion Analysis - Velocity01:24

Relative Motion Analysis - Velocity

A stroke engine has a slider-crank mechanism that converts rotational motion from the crank into linear motion of the slider or vice versa. This mechanism consists of three main parts: the crank, the connecting rod, and the slider.
When an external force is exerted, it sets the crank into a rotational movement. This, in turn, instigates the motion of the connecting rod, leading to what is referred to as a general plane motion. This process involves two key points - point A on the connecting rod...
Accelerating Fluids01:17

Accelerating Fluids

When a fluid is in constant acceleration, the pressure and buoyant force equations are modified. Suppose a beaker is placed in an elevator accelerating upward with a constant acceleration, a. In the beaker, assume there is a thin cylinder of height h with an infinitesimal cross-sectional area, ΔS.
The motion of the liquid within this infinitesimal cylinder is considered to obtain the pressure difference. Three vertical forces act on this liquid:
Precipitate Formation and Particle Size Control01:16

Precipitate Formation and Particle Size Control

In precipitation gravimetry, the precipitating agent should react specifically or selectively with the analyte. While a specific reagent reacts with the analyte alone, a selective reagent can react with a limited number of chemical species.
The obtained precipitate should be either a pure substance of known composition or easily converted to one by a simple process, such as ignition or drying. In addition, the precipitate should be insoluble and easily filterable. In general, filterability...
Relative Motion Analysis - Acceleration01:10

Relative Motion Analysis - Acceleration

A slider-crank mechanism converts rotational motion from the crank into linear motion of the slider or vice versa. This mechanism consists of three main parts: the crank, the connecting rod, and the slider. The movement of the slider-crank is an example of general plane motion as the fluctuating angle between the crank and the connecting rod. Consider a segment AB where point A is at the end of the slider and point B is on the diametrically opposite end to point A, on a crack. The variance in...
Relative Motion Analysis using Rotating Axes01:25

Relative Motion Analysis using Rotating Axes

Consider a component AB undergoing a linear motion. Along with a linear motion, point B also rotates around point A. To comprehend this complex movement, position vectors for both points A and B are established using a stationary reference frame.
However, to express the relative position of point B relative to point A, an additional frame of reference, denoted as x'y', is necessary. This additional frame not only translates but also rotates relative to the fixed frame, making it instrumental in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "Efficacy and safety of prophylaxis and treatment of bleeding events with a novel fibrinogen concentrate from human plasma in patients with congenital fibrinogen deficiency" [Thromb. Res. volume 259 (2026) https://doi.org/10.1016/j.thromres.2026.109616].

Thrombosis research·2026
Same author

Efficacy and safety of prophylaxis and treatment of bleeding events with a novel fibrinogen concentrate from human plasma in patients with congenital fibrinogen deficiency.

Thrombosis research·2026
Same author

Synergistic aligned neuronal and vascular growth inside 3D-PEG-Anisogels utilizing a triple-co-culture.

Materials today. Bio·2026
Same author

Exploring compartmentalized jet polymerization for novel rod-shaped microgels and their potential in tissue engineering applications.

Biomaterials·2025
Same author

Pharmacokinetics, Hemostatic Efficacy, and Safety of a New Human Fibrinogen Concentrate in Adult and Pediatric Patients with Congenital Fibrinogen Deficiency.

Thrombosis and haemostasis·2025
Same author

PSMA response evaluation in follow-up PSMA-PET/CT after stereotactic ablative body radiotherapy (SABR) for oligometastases in prostate cancer.

Clinical and translational radiation oncology·2025

Related Experiment Video

Updated: May 18, 2026

Longitudinal Measurement of Extracellular Matrix Rigidity in 3D Tumor Models Using Particle-tracking Microrheology
11:11

Longitudinal Measurement of Extracellular Matrix Rigidity in 3D Tumor Models Using Particle-tracking Microrheology

Published on: June 10, 2014

Splinelike interpolation in particle tracking microrheology.

Timo Maier1, Heike Boehm, Tamás Haraszti

  • 1Max Planck Institute for Intelligent Systems, Heisenbergstrasse 3, 70569 Stuttgart, Germany.

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
|September 26, 2012
PubMed
Summary

This study presents a new method for converting time-dependent creep compliance to frequency-dependent shear modulus in microrheology. It uses segmentwise fitting and numerical conversion for improved accuracy, especially for complex biopolymer gels.

More Related Videos

In Situ Mapping of the Mechanical Properties of Biofilms by Particle-tracking Microrheology
12:58

In Situ Mapping of the Mechanical Properties of Biofilms by Particle-tracking Microrheology

Published on: December 4, 2015

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions
11:38

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Published on: April 19, 2018

Related Experiment Videos

Last Updated: May 18, 2026

Longitudinal Measurement of Extracellular Matrix Rigidity in 3D Tumor Models Using Particle-tracking Microrheology
11:11

Longitudinal Measurement of Extracellular Matrix Rigidity in 3D Tumor Models Using Particle-tracking Microrheology

Published on: June 10, 2014

In Situ Mapping of the Mechanical Properties of Biofilms by Particle-tracking Microrheology
12:58

In Situ Mapping of the Mechanical Properties of Biofilms by Particle-tracking Microrheology

Published on: December 4, 2015

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions
11:38

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Published on: April 19, 2018

Area of Science:

  • Materials Science
  • Biophysics
  • Rheology

Background:

  • Particle tracking microrheology relies on converting time-dependent creep compliance to frequency-dependent complex shear modulus.
  • Traditional methods of fitting functions to the entire time range can be insufficient for complex materials like biopolymer gels.
  • Segmentwise fitting is often necessary but poses challenges in analytical transformation and derivative continuity.

Purpose of the Study:

  • To develop a robust method for converting creep compliance to complex shear modulus for materials exhibiting different time-dependent behaviors.
  • To address the limitations of analytical transformations and ensure continuity in segmentwise fitting.
  • To improve the accuracy and reliability of microrheology data analysis.

Main Methods:

  • Segmentwise fitting of creep compliance data across different time regimes.
  • Numerical conversion of fitted functions to frequency-dependent complex shear modulus.
  • Utilizing interpolation techniques to ensure smooth transitions between fitted segments.
  • Implementing a dynamic sampling technique for accuracy control.

Main Results:

  • A novel method combining segmentwise fitting and numerical conversion was successfully developed.
  • The proposed method ensures better continuity of the first derivative compared to traditional spline methods.
  • Interpolation and dynamic sampling techniques were shown to improve the accuracy of the complex shear modulus calculation.

Conclusions:

  • The presented method offers a reliable approach for rheological analysis of complex materials, including biopolymer gels.
  • This technique enhances the accuracy of complex shear modulus determination in particle tracking microrheology.
  • The dynamic sampling strategy provides a means to control the precision of the rheological measurements.