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Intrinsic dissolution rates of tablet filler-binders and their influence on the dissolution of drugs from tablet
A D Koparkar1, L L Augsburger, R F Shangraw
1CIBA-GEIGY Corporation, Summit, New Jersey 07901.
Pharmaceutical Research
|January 1, 1990
Abstract:
Intrinsic dissolution rates were determined for different grades of commonly used calcium salt fillers and lactose. Typical tablet formulations of low-dose drugs were studied to determined the influence of this property on drug dissolution.