Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Short-distance Transport of Resources02:12

Short-distance Transport of Resources

Short-distance transport refers to transport that occurs over a distance of just 2-3 cells, crossing the plasma membrane in the process. Small uncharged molecules, such as oxygen, carbon dioxide, and water, can diffuse across the plasma membrane on their own. In contrast, ions and larger molecules require the assistance of transport proteins due to their charge or size. Transport across membranes also occurs within individual cells, playing a variety of essential roles for the plant as a whole.
Carrier-Mediated Transport01:06

Carrier-Mediated Transport

Carrier-mediated transport is a pivotal process in drug absorption, particularly for lipid-insoluble drugs, and encompasses facilitated diffusion and active transport. Facilitated diffusion allows drugs to move along their concentration gradient without energy expenditure, while active transport utilizes ATP to drive drug movement against this gradient.
Active transport involves two types of membrane-spanning transporters: uptake and efflux. Uptake transporters are expressed in the small...
Reynolds Transport Theorem01:24

Reynolds Transport Theorem

The Reynolds transport theorem provides a framework to relate the time rate of change of an extensive property within a system to that in a control volume, which is crucial for analyzing fluid dynamics. Extensive properties, such as mass, velocity, acceleration, temperature, and momentum, can be expressed in terms of the mass of a fluid portion. These properties are called extensive because they depend on the system's size, while intensive properties are their corresponding values per unit mass.
Pore Transport and Ion-Pair Transport01:17

Pore Transport and Ion-Pair Transport

Pore transport and ion-pair formation are critical mechanisms for the absorption and distribution of drugs in the body.
Pore transport, also known as convective transport, is a process where small molecules like urea, water, and sugars rapidly cross cell membranes as though there were channels or pores in the membrane. Although direct microscopic evidence is limited  but the concept of pores or channels is widely accepted based on physiological evidence. Despite the lack of direct microscopic...
Nonlinear Pharmacokinetics: Role of Transporters01:27

Nonlinear Pharmacokinetics: Role of Transporters

A drug's nonlinear kinetics can be influenced by a diverse range of transporter proteins that serve as crucial players in drug distribution. These transporters, found within cells, can enhance or reduce local drug concentrations by facilitating the influx or efflux of drugs. For instance, the expression of xenobiotic transporters can be influenced by factors such as age and gender, potentially impacting the linearity of drug response.
Polymorphisms occurring in drug transporters can alter...
Membrane Transporters01:31

Membrane Transporters

Transporters are essential membrane transport proteins with functions related to cell nutrition, homeostasis, communication, etc. Approximately 7% of all genes in the human genome code for transporters or transporter-related proteins.
Transporters are mainly composed of alpha-helices, built from bundles of ten or more helices traversing the plasma membrane. The solute-binding sites are located midway, where some of the helices are broken or distorted, making space for the binding site through...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The HIV capsid mimics karyopherin engagement of FG-nucleoporins.

Nature·2024
Same author

The role of complexity for digital twins of cities.

Nature computational science·2024
Same author

Spectroscopic confirmation of a mature galaxy cluster at a redshift of 2.

Nature·2020
Same author

Investigating virtual reality navigation in amnestic mild cognitive impairment using fMRI.

Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition·2015
Same author

Nonlinear growth and condensation in multiplex networks.

Physical review. E, Statistical, nonlinear, and soft matter physics·2014
Same author

Executive function processes mediate the impact of working memory impairment on intelligence in schizophrenia.

European psychiatry : the journal of the Association of European Psychiatrists·2014
Same journal

Erratum: Bacterial Turbulence at Compressible Fluid Interfaces [Phys. Rev. Lett. 136, 138301 (2026)].

Physical review letters·2026
Same journal

Unveiling Light-Quark Yukawa Flavor Structure via Dihadron Fragmentation at Lepton Colliders.

Physical review letters·2026
Same journal

Adaptable Route to Fast Coherent State Transport via Bang-Bang-Bang Protocols.

Physical review letters·2026
Same journal

Topological Transition and Emergence of Elasticity of Dislocation in Skyrmion Lattice: Beyond Kittel's Magnetic-Polar Analogy.

Physical review letters·2026
Same journal

Pound-Drever-Hall Method for Superconducting-Qubit Readout.

Physical review letters·2026
Same journal

Coupling a ^{73}Ge Nuclear Spin to an Electrostatically Defined Quantum Dot in Silicon.

Physical review letters·2026
See all related articles

Related Experiment Video

Updated: May 18, 2026

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

Transport on coupled spatial networks.

R G Morris1, M Barthelemy

  • 1Institut de Physique Théorique, CEA, CNRS-URA, Gif-sur-Yvette, France.

Physical Review Letters
|September 26, 2012
PubMed
Summary
This summary is machine-generated.

This study introduces a new measure for network utility in interdependent spatial systems. Optimal network performance depends on system coupling, source-sink distribution, and traffic congestion.

More Related Videos

Analyzing the Size, Shape, and Directionality of Networks of Coupled Astrocytes
10:10

Analyzing the Size, Shape, and Directionality of Networks of Coupled Astrocytes

Published on: October 4, 2018

Optimizing Visualization of Axonal Transport of Endogenous Cargo by Fluorescence Microscopy in Living Caenorhabditis elegans
05:47

Optimizing Visualization of Axonal Transport of Endogenous Cargo by Fluorescence Microscopy in Living Caenorhabditis elegans

Published on: February 16, 2024

Related Experiment Videos

Last Updated: May 18, 2026

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

Analyzing the Size, Shape, and Directionality of Networks of Coupled Astrocytes
10:10

Analyzing the Size, Shape, and Directionality of Networks of Coupled Astrocytes

Published on: October 4, 2018

Optimizing Visualization of Axonal Transport of Endogenous Cargo by Fluorescence Microscopy in Living Caenorhabditis elegans
05:47

Optimizing Visualization of Axonal Transport of Endogenous Cargo by Fluorescence Microscopy in Living Caenorhabditis elegans

Published on: February 16, 2024

Area of Science:

  • Network Science
  • Complex Systems
  • Spatial Analysis

Background:

  • Real-world systems, such as transportation and communication networks, are often interdependent rather than isolated.
  • Understanding how coupled spatial networks function is crucial for optimizing their performance and resilience.

Purpose of the Study:

  • To develop a novel measure of utility for coupled spatial networks.
  • To investigate how network coupling, source-sink distribution, and routing strategies influence overall system utility.

Main Methods:

  • Development of a new utility measure for coupled spatial systems.
  • Simulation using a toy model to explore various coupling scenarios.
  • Analysis of network behavior under different source-sink distributions and coupling strengths.

Main Results:

  • Identified two distinct regimes in coupled spatial networks based on source-sink configurations.
  • In many-to-few sink systems, maximum coupling and minimized shortest path yield highest utility.
  • In many-to-many sink systems, optimal coupling balances path length with traffic congestion.

Conclusions:

  • Network utility in coupled spatial systems is sensitive to the interplay between coupling strength and source-sink distribution randomness.
  • The findings highlight the need to consider congestion effects beyond simple topological measures for efficient network design.
  • The proposed utility measure offers insights into optimizing interdependent spatial systems in diverse real-world applications.