Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Structure of Lipids

Structure of Lipids

Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic birds and...

Structure of Lipids

Structure of Lipids

Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic birds and...

Structure of Lipids

Structure of Lipids

Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic birds and...

Biosynthesis of Lipids

Biosynthesis of Lipids

Microbial membranes exhibit remarkable diversity in lipid composition, reflecting evolutionary adaptations to various environmental conditions. The three domains of life—Bacteria, Archaea, and Eukarya—synthesize membrane lipids through distinct biosynthetic pathways, leading to fundamental structural differences that impact membrane stability, function, and adaptability.Fatty Acid-Based Lipids in Bacteria and EukaryaBacteria and eukaryotes share a common fatty acid biosynthesis pathway, which...

Lipid-derived Compounds in the Human Body

Lipid-derived Compounds in the Human Body

Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin, delayed...

What are Lipids?

What are Lipids?

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Indoor air quality and its effects on lung function and respiratory symptoms among textile spinning mill workers in India.

Work (Reading, Mass.)·2026

Same author

Brain Organoids, Lessons from Fetal Neocortex Formation, and Rational Design for Quality Control.

bioRxiv : the preprint server for biology·2026

Same author

Oncogenic cell fate decision in breast epithelial cells I: growth factors and mechanisms.

Research square·2026

Same author

Performance evaluation of an EEG-guided robotic glove with machine learning models for hand rehabilitation in injured athletes.

Journal of back and musculoskeletal rehabilitation·2026

Same author

Single-cell transcriptional landscape of muscle-derived stem/progenitor cells reveals hallmarks of aging and rejuvenation.

bioRxiv : the preprint server for biology·2026

Same author

Differential peripheral immune dynamics underlie therapeutic response to chemotherapy and chemoimmunotherapy in triple-negative breast cancer.

bioRxiv : the preprint server for biology·2026

Search research articles

Related Experiment Video

Updated: May 18, 2026

Curation of Computational Chemical Libraries Demonstrated with Alpha-Amino Acids

Curation of Computational Chemical Libraries Demonstrated with Alpha-Amino Acids

Published on: April 13, 2022

Template-based combinatorial enumeration of virtual compound libraries for lipids.

Manish Sud¹, Eoin Fahy, Shankar Subramaniam

¹San Diego Supercomputer Center, University of California San Diego, 9500, Gilman Drive, La Jolla, CA 92032, USA. msud@san.rr.com.

Journal of Cheminformatics

|September 26, 2012

Summary

This summary is machine-generated.

LipidMapsTools software enables consistent 2D structure generation for virtual lipid libraries. This open-source package provides a standardized method for enumerating lipid compounds, improving data representation.

More Related Videos

A Bilingual Computational Workflow for Identifying Potential PLK1 Inhibitors in American Sign Language and English

A Bilingual Computational Workflow for Identifying Potential PLK1 Inhibitors in American Sign Language and English

Published on: April 3, 2026

Isolation of Lipoprotein Particles from Chicken Egg Yolk for the Study of Bacterial Pathogen Fatty Acid Incorporation into Membrane Phospholipids

Isolation of Lipoprotein Particles from Chicken Egg Yolk for the Study of Bacterial Pathogen Fatty Acid Incorporation into Membrane Phospholipids

Published on: May 15, 2019

Related Experiment Videos

Last Updated: May 18, 2026

Curation of Computational Chemical Libraries Demonstrated with Alpha-Amino Acids

Curation of Computational Chemical Libraries Demonstrated with Alpha-Amino Acids

Published on: April 13, 2022

A Bilingual Computational Workflow for Identifying Potential PLK1 Inhibitors in American Sign Language and English

A Bilingual Computational Workflow for Identifying Potential PLK1 Inhibitors in American Sign Language and English

Published on: April 3, 2026

Isolation of Lipoprotein Particles from Chicken Egg Yolk for the Study of Bacterial Pathogen Fatty Acid Incorporation into Membrane Phospholipids

Isolation of Lipoprotein Particles from Chicken Egg Yolk for the Study of Bacterial Pathogen Fatty Acid Incorporation into Membrane Phospholipids

Published on: May 15, 2019

Area of Science:

Computational chemistry
Bioinformatics
Lipidomics

Background:

Existing software for virtual library enumeration lacks control over 2D structure layout.
Inconsistent 2D representations hinder standardization in computational chemistry and lipidomics.

Purpose of the Study:

To develop a software package, LipidMapsTools, for template-based combinatorial enumeration of virtual lipid compound libraries.
To ensure consistent and standardized 2D structure representation for enumerated lipids.

Main Methods:

LipidMapsTools utilizes pre-defined lipid templates and chain abbreviations for enumeration.
The software adheres to the LIPID MAPS consortium's framework for lipid structure representation.
Enumeration is template-based, differing from scaffold-and-R-group methods.

Main Results:

LipidMapsTools generates virtual lipid libraries with consistent 2D structures.
The software is lightweight, fast, and has no external dependencies.
It provides a standardized approach to virtual lipid library creation.

Conclusions:

LipidMapsTools offers a novel solution for controlled 2D layout in virtual lipid library enumeration.
The open-source package promotes standardization and accessibility in lipid research.
This tool facilitates consistent data representation in lipidomics and computational drug discovery.