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Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
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Sexually transmitted diseases syndromic approach: proctitis.

G Zuccati1, L Tiradritti, E Lorenzoni

  • 1Department of Critical Care Medicine and Surgery, University of Florence, Florence, Italy. giuliano.zuccati@unifi.it

Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Societa Italiana Di Dermatologia E Sifilografia
|September 26, 2012
PubMed
Summary

Infectious proctitis cases are increasing, particularly in men who have sex with men, often linked to sexually transmitted infections. Prompt diagnosis and treatment are crucial for managing this condition.

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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Sexual Health

Background:

  • Proctitis is commonly linked to inflammatory bowel diseases (IBD).
  • A notable rise in infectious proctitis incidence has been observed in the past decade, especially among men who have sex with men (MSM).
  • This increase may be attributed to higher rates of receptive anal intercourse and a surge in sexually transmitted infections (STIs).

Purpose of the Study:

  • To highlight the growing concern of infectious proctitis.
  • To emphasize the role of STIs in proctitis diagnosis.
  • To outline diagnostic and treatment considerations for infectious proctitis.

Main Methods:

  • Review of current literature and clinical observations regarding proctitis.
  • Emphasis on patient history and physical examination.
  • Discussion of diagnostic tools including endoscopy, histology, serology, culture, and PCR.

Main Results:

  • Sexually transmitted infections like Chlamydia trachomatis, Neisseria gonorrhoeae, Herpes simplex virus, and Treponema pallidum are significant causes of infectious proctitis.
  • Recent outbreaks of lymphogranuloma venereum underscore the importance of considering STIs.
  • Symptoms encompass rectal bleeding, discharge, pain, ulcers, and systemic signs like fever and lymphadenopathy.

Conclusions:

  • Infectious proctitis, driven by STIs, requires careful consideration in differential diagnoses.
  • Prompt and accurate diagnosis through clinical evaluation and specific tests is essential.
  • Empirical or targeted antibiotic/antiviral treatment, alongside management of coinfections, HIV status, and sexual partners, is critical.