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[Perineural dissemination in labial carcinoma]
L Naval1, J Fraga, C López Elzaudia
1Service de Chirurgie Maxillo-faciale, Hospital de la Princesa, Madrid, Espagne
Revue De Stomatologie Et De Chirurgie Maxillo-Faciale
|January 1, 1990
Summary
Lip carcinomas can extend to the mandible via the mental nerve, causing peripheral neuropathy. This progression, observed over one to four years, highlights a critical diagnostic and treatment challenge.
Area of Science:
- Oral oncology
- Neurology
- Surgical pathology
Background:
- Lip carcinoma is a common malignancy.
- Nerve involvement can occur but is infrequently documented.
- Mandibular invasion presents advanced disease.
Observation:
- Four cases of lip carcinoma with mandibular extension are presented.
- Progression occurred over 1-4 years.
- Mental nerve involvement was noted, leading to peripheral neuropathy.
Findings:
- Lip cancer invasion to the mandible can occur through the mental nerve.
- Peripheral neuropathy is a clinical sign of this advanced spread.
- Multiple peripheral neuropathy was observed in one case.
Implications:
- Early detection of lip carcinoma is crucial to prevent mandibular invasion.
- Neurological symptoms may indicate advanced cancer spread.
- Multidisciplinary management is essential for these complex cases.