Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Intestinal Obstruction II: Pathophysiology

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...

Diverticular Disease of the Colon

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...

Appendicitis

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

Intestinal Obstruction I: Introduction

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...

Hiatal Hernia

Hiatal Hernia

A hiatal hernia is the abnormal protrusion of the stomach or other abdominal organs through the esophageal hiatus of the diaphragm into the thoracic cavity.Normally, the gastroesophageal junction (GEJ) lies below the diaphragm and is supported by the phrenoesophageal membrane, the diaphragmatic crura, and connective tissues. Weakening of these structures—due to aging, congenital defects like a short esophagus, or increased intra-abdominal pressure from coughing, obesity, pregnancy, or heavy...

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Mitochondrial D-Loop Region Methylation Is Not Altered in Children with Autism Spectrum Disorder.

Epigenomes·2026

Same author

AI-based autism identification from hyperspectral imaging detection of oxidative stress in pediatric red blood cells.

Communications medicine·2026

Same author

Italian Expert Consensus on the Efficacy and Safety of High Doses of Incobotulinum Toxin A (Bocouture<sup>®</sup>) in a Full-Face Approach Based on the Electromyographic Analysis.

Dermatology and therapy·2026

Same author

Double blind-ending ureter: diagnostic challenges and robotic-assisted surgical management-case report.

The Canadian journal of urology·2026

Same author

Enhancing the Informed Consent Process in Pediatric Surgery Through an Educational Smartphone Application: Feasibility and Outcomes.

International journal of telemedicine and applications·2026

Same author

Iron-Catalyzed C-H Alkylative Ring Openings of Oxabicyclic Alkenes.

Organic letters·2026

Search research articles

Related Experiment Video

Updated: May 18, 2026

Multimodality Diagnosis of Mesenteric Ischemia

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

A mesenteric hernia complicated with a triple necrotic volvulus.

Davide Tassinari¹, Stefano Santoro, Filippo Bernardi

¹Paediatric Emergency Department, S.Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy. davide.tassinari@aosp.bo.it

BMJ Case Reports

|September 26, 2012

Summary

A pediatric patient experienced severe abdominal pain due to a rare triple volvulus, a twisting of the small intestine. Prompt surgical intervention was crucial to resect necrotic bowel and save the child's life.

Related Experiment Videos

Last Updated: May 18, 2026

Multimodality Diagnosis of Mesenteric Ischemia

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

Area of Science:

Pediatric Surgery
Gastrointestinal Surgery
Abdominal Emergencies

Background:

Recurrent abdominal pain in children can indicate serious underlying pathology.
Early diagnosis and management of pediatric abdominal emergencies are critical.

Observation:

A 6-year-old girl presented with acute colicky abdominal pain and a history of recurrent admissions.
Clinical examination revealed no peritoneal signs, but blood tests showed elevated white blood cells.
Abdominal X-ray indicated small bowel obstruction, and the patient rapidly deteriorated into shock.

Findings:

Surgical exploration revealed a triple volvulus with bowel loops herniated through a mesenteric defect.
Necrotic bowel segments were identified, necessitating resection.

Implications:

This case highlights the importance of considering rare causes of abdominal pain in children, even with non-specific initial findings.
Timely surgical intervention is vital for managing complex gastrointestinal emergencies like triple volvulus.
Mesenteric defects can predispose to volvulus and require careful surgical consideration.