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Amitriptyline cream ingestion in a 1-year-old boy

Nathalie S M Lak1, Mirte M Malingre, Paul H G Hogeman

  • 1Meander Medical Centre, Ringweg Randenbroek 110, 3816 CP Amersfoort, the Netherlands.

Pediatrics
|September 26, 2012
PubMed

Insights

Amitriptyline cream intoxication in a child caused drowsiness and cardiac issues. Prompt monitoring led to a full recovery within 24 hours, highlighting cream safety concerns.

Area of Science:

  • Pediatric Toxicology
  • Dermatology
  • Clinical Case Reports

Background:

  • Amitriptyline, an antidepressant and neuropathic pain medication, is typically administered orally.
  • Topical amitriptyline cream represents a novel formulation with less established safety data, particularly in pediatric populations.
  • Pediatric amitriptyline exposure can lead to severe systemic effects, including central nervous system and cardiovascular complications.

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