Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hemorrhagic Stroke l: Introduction

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...

Hemorrhagic Stroke ll: Pathophysiology

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...

Stroke: Introduction and Types

Stroke: Introduction and Types

A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...

Ischemic Stroke ll: Pathophysiology

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...

Ischemic Stroke l: Introduction

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Fatal Fat Embolism Syndrome Without Recognized Fracture in Patients With Duchenne Muscular Dystrophy: Two Case Reports.

Pediatric neurology·2026

Same author

Advances in Stroke 2026: Treatments-Preventive.

Stroke·2026

Same author

Nonoperative management of patients with symptomatic carotid stenosis.

Seminars in vascular surgery·2026

Same author

Barriers, Attitudes, and Solutions for Brain Health Research Training in LMICs: A Trainee Cross-Sectional Study in Uganda.

Advances in medical education and practice·2026

Same author

Demographics and Clinical Correlates of Blood Pressure Among Ugandans at Risk for Stroke.

Journal of neurology research·2026

Same author

Nonketotic Hyperglycinemia in Central and Appalachian Kentucky.

Journal of child neurology·2026

Search research articles

Related Experiment Video

Updated: May 18, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

Poststroke hypertension in Africa.

Martin Kaddumukasa¹, Edward Ddumba, Pamela Duncan

¹Makerere University, College of Health Sciences, Kampala, Uganda.

|September 27, 2012

Summary

This summary is machine-generated.

Hypertension is common in Ugandans, particularly those with a history of stroke. Effective blood pressure control requires addressing factors beyond patient knowledge.

More Related Videos

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

Real-Time Monitoring and Modulation of Blood Pressure in a Rabbit Model of Ischemic Stroke

Real-Time Monitoring and Modulation of Blood Pressure in a Rabbit Model of Ischemic Stroke

Published on: February 10, 2023

Related Experiment Videos

Last Updated: May 18, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

Real-Time Monitoring and Modulation of Blood Pressure in a Rabbit Model of Ischemic Stroke

Real-Time Monitoring and Modulation of Blood Pressure in a Rabbit Model of Ischemic Stroke

Published on: February 10, 2023

Area of Science:

Cardiology
Neurology
Public Health

Background:

Hypertension prevalence and knowledge in African stroke survivors are poorly understood.
Assessing hypertension and its related knowledge is crucial for stroke prevention and management in Uganda.

Purpose of the Study:

To determine the frequency of hypertension and its control among stroke patients and controls in Uganda.
To evaluate hypertension-related knowledge in these groups and identify associated factors.

Main Methods:

A comparative study involving 157 stroke patients and 149 stroke-free controls.
Data collection included demographics, clinical characteristics, and a hypertension knowledge questionnaire.
Logistic regression analysis identified factors associated with blood pressure control and knowledge.

Main Results:

Higher hypertension prevalence (69.4%) was observed in stroke patients compared to controls (54.7%).
Stroke patients had lower odds of good blood pressure control and hypertension knowledge.
Younger age, good knowledge, and poor medication adherence were linked to poorer blood pressure control.

Conclusions:

Hypertension is highly prevalent in the Ugandan population, with or without a history of stroke.
Effective blood pressure management necessitates identifying barriers beyond patient knowledge.
Further research is needed to improve hypertension control strategies in Uganda.