A case report: Multaq-induced leukocytoclastic vasculitis.

Area of Science:

• Dermatology
• Cardiology
• Pharmacology

Background:

• Atrial fibrillation is a common cardiac arrhythmia.
• Multaq (dronedarone) is a medication used to treat atrial fibrillation.
• Leukocytoclastic vasculitis (LV) is a form of vasculitis characterized by inflammation of small blood vessels.

Observation:

• A 71-year-old male presented with a worsening lower extremity rash.
• The patient had recently been prescribed Multaq for paroxysmal atrial fibrillation.
• Biopsy confirmed leukocytoclastic vasculitis.

Findings:

• Other potential causes of leukocytoclastic vasculitis were ruled out.
• Rash is a known potential side effect of Multaq.
• This represents the first documented case of likely Multaq-induced leukocytoclastic vasculitis.

Implications:

• Healthcare providers should consider Multaq as a potential cause of leukocytoclastic vasculitis.
• Patients on Multaq therapy should be monitored for dermatological adverse events.
• Prompt recognition and management of drug-induced vasculitis are crucial for patient outcomes.