Related Experiment Video
Updated: May 18, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Electronic coupling between two amine redox sites through the 5,5'-positions of metal-chelating 2,2'-bipyridines
Hai-Jing Nie1, Xialing Chen, Chang-Jiang Yao
1Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China.
Abstract:
Electron delocalization of new mixed-valent (MV) systems with the aid of lateral metal chelation is reported. 2,2'-Bipyridine (bpy) derivatives with one or two appended di-p-anisylamino groups on the 5,5'-positions and a coordinated [Ru(bpy)(2)] (bpy = 2,2'-bipyridine), [Re(CO)(3)Cl], or [Ir(ppy)(2)] (ppy = 2-phenylpyridine) component were prepared. The single-crystal molecular structure of the bis-amine ligand without metal chelation is presented. The electronic properties of these complexes were studied and compared by electrochemical and spectroscopic techniques and DFT/TDDFT calculations. Compounds with two di-p-anisylamino groups were oxidized by a chemical or electrochemical method and monitored by near-infrared (NIR) absorption spectral changes. Marcus-Hush analysis of the resulting intervalence charge-transfer transitions indicated that electron coupling of these mixed-valent systems is enhanced by metal chelation and that the iridium complex has the largest coupling. TDDFT calculations were employed to interpret the NIR transitions of these MV systems.
More Related Videos
07:07Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
Published on: March 12, 2015
11:04Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
Published on: September 7, 2019
Related Concept Videos
Complexation Equilibria: The Chelate Effect
Metal-Ligand Bonds
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
Aryldiazonium Salts to Azo Dyes: Diazo Coupling
Complexometric Titration: Ligands
Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...
Structural Isomerism
Isomers are different chemical species that have the same chemical formula. Structural isomerism of coordination compounds can be divided into two subcategories, the linkage isomers and coordination-sphere isomers.
Linkage isomers occur when the coordination compound contains a ligand that can bind to the transition metal center through two different atoms. For example, the CN− ligand can bind through the carbon atom or through the nitrogen atom. Similarly, SCN− can be...