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Severe malaria in sudanese children: clinical aspects and prognosis in hospitilized patients

Zeidan A Zeidan1, Elkhir M Kojal, Ali B Habour

  • 1University of Khartoum, Sudan.

Journal of Family & Community Medicine
|September 27, 2012
PubMed

Insights

Severe malaria in Sudanese children is a significant threat, with delayed treatment and severe symptoms increasing mortality risk. Improving healthcare management and parental awareness can reduce deaths from this disease.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Epidemiology

Background:

  • Severe malaria poses a significant health burden in children in Sudan.
  • Understanding its epidemiology and risk factors is crucial for effective intervention.

Purpose of the Study:

  • To assess the epidemiology, clinical presentations, management, outcomes, and risk factors of severe malaria in children across four Sudanese hospitals.
  • To identify factors contributing to mortality and evaluate case management performance.

Main Methods:

  • A prospective follow-up study was conducted in four hospitals in Sudan: Omdurman Paediatrics Hospital (Khartoum) and hospitals in Madani, Gadarif, and Sennar.
  • Data on severe malaria admissions, clinical features, treatment, and outcomes were collected.

Main Results:

  • Severe malaria accounted for 21% of pediatric admissions and 12% of outpatient malaria cases.
  • The case fatality rate was 2.6%, with delayed treatment increasing the risk of death fourfold.
  • Coma, inability to sit or eat, and hyperpyrexia were associated with increased mortality.

Conclusions:

  • Improving healthcare management, resource allocation, and training programs can reduce severe malaria deaths.
  • Enhancing parental awareness regarding early treatment seeking is vital to prevent unnecessary child mortality.
Abstract

Keywords:
Case fatality rateSevere malariaSevere malaria management scoring system

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