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Colonic mucosa-associated lymphoid tissue lymphoma
Risaburo Akasaka1, Toshimi Chiba, Amit K Dutta
1Division of Gastroenterology and Hepatology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan.
Case Reports in Gastroenterology
|September 27, 2012
Summary
Colonic mucosa-associated lymphoid tissue (MALT) lymphomas are rare gastrointestinal tumors. This study presents four cases, highlighting varied endoscopic appearances and successful treatment outcomes with radiation, endoscopic resection, or surgery.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Colonic mucosa-associated lymphoid tissue (MALT) lymphomas are uncommon neoplasms.
- Definitive treatment strategies for colonic MALT lymphoma are not well-established.
- Typical endoscopic findings include elevated, polypoid, or solitary lesions, sometimes with abnormal vascularity.
Observation:
- Four cases of colonic MALT lymphoma are presented.
- Lesions varied in appearance and location, including rectal elevated lesions and cecal polyps.
- Diagnostic methods involved biopsy, endoscopic ultrasonography (EUS), and magnification endoscopy.
Findings:
- Case 1: Rectal lesion treated with radiation therapy resulted in complete resolution.
- Case 2: Cecal polyp treated with endoscopic mucosal resection showed no recurrence after 6 years.
- Case 3: Sigmoid lesion treated with sigmoidectomy.
- Case 4: Rectal lesion treated with endoscopic submucosal dissection.
Implications:
- Increased awareness of colonic MALT lymphoma is crucial for accurate diagnosis and management.
- Diverse therapeutic approaches, including radiation, endoscopic resection, and surgery, can be effective.
- Multimodality assessment including endoscopy, EUS, and histopathology is important for optimal patient care.
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