Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Investigation of Disease Outbreaks

Investigation of Disease Outbreaks

Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...

Colonisation of Pathogens

Colonisation of Pathogens

Pathogen colonization of host tissues is a critical step in the development of infectious diseases. Various pathogenic microorganisms, including bacteria, fungi, viruses, and protozoa, have evolved complex strategies to attach to, invade, and persist within host environments. These mechanisms enable pathogens to establish infections, evade immune responses, and resist antimicrobial treatments.Attachment to Host CellsIn bacteria, colonization typically begins with adherence to host epithelial...

Microbial Interactions: Cooperation

Microbial Interactions: Cooperation

Microbial cooperation involves beneficial interactions in which different species work together for individual or mutual advantage. These interactions can profoundly influence ecological dynamics and evolutionary processes, and they are essential to many pathogenic and symbiotic relationships.Nematode–Bacteria CooperationA striking example is the relationship between the Gram-negative bacterium Xenorhabdus nematophila and the parasitic nematode Steinernema carpocapsae. Juvenile nematodes...

Pulmonary Tuberculosis III

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:

EPS and iPS Cells in Disease Research

EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...

Sputum Studies II: Culture and Sensitivity

Sputum Studies II: Culture and Sensitivity

Description
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

QTFPred: robust high-performance quantum machine learning modeling that predicts main and cooperative transcription factor bindings with base resolution.

Briefings in bioinformatics·2025

Same author

Sonochemiluminescence of lucigenin using amines as coreactant: Reactivity and mechanism studies.

Ultrasonics sonochemistry·2020

Same author

Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae.

Nature communications·2018

Same author

Whole genome sequencing distinguishes between relapse and reinfection in recurrent leprosy cases.

PLoS neglected tropical diseases·2017

Same author

qPCR-High resolution melt analysis for drug susceptibility testing of Mycobacterium leprae directly from clinical specimens of leprosy patients.

PLoS neglected tropical diseases·2017

Same author

Profiling of Intracellular Metabolites: An Approach to Understanding the Characteristic Physiology of Mycobacterium leprae.

PLoS neglected tropical diseases·2016

Search research articles

Related Experiment Video

Updated: May 18, 2026

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

Published on: March 23, 2014

[Collaboration between Korea and Japan for basic research on leprosy].

Masanori Matsuoka¹

¹Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan. matsuoka@nih.go.jp

Nihon Hansenbyo Gakkai Zasshi = Japanese Journal of Leprosy : Official Organ of the Japanese Leprosy Association

|September 28, 2012

Summary

Leprosy research continues in Japan and Korea despite declining case detection. Ongoing and prospective studies focus on drug resistance, diagnostics, neuropathy, and potential vaccines, fostering international collaboration.

More Related Videos

In Vivo Imaging Uncovers the Migratory Behavior of Leukocytes within the Joints

In Vivo Imaging Uncovers the Migratory Behavior of Leukocytes within the Joints

Published on: December 9, 2025

Establishment of an Extracellular Acidic pH Culture System

Establishment of an Extracellular Acidic pH Culture System

Published on: November 19, 2017

Related Experiment Videos

Last Updated: May 18, 2026

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

Published on: March 23, 2014

In Vivo Imaging Uncovers the Migratory Behavior of Leukocytes within the Joints

In Vivo Imaging Uncovers the Migratory Behavior of Leukocytes within the Joints

Published on: December 9, 2025

Establishment of an Extracellular Acidic pH Culture System

Establishment of an Extracellular Acidic pH Culture System

Published on: November 19, 2017

Area of Science:

Microbiology and Immunology
Epidemiology
Pharmacology

Context:

Leprosy case detection has significantly decreased in Japan and Korea.
Despite challenges, research activities on leprosy remain active in both nations.
There is a growing body of knowledge on leprosy in Japan and Korea.

Purpose:

To review ongoing basic leprosy research in Japan.
To propose prospective studies for future leprosy research.
To explore potential Japan-Korea collaboration for leprosy control.

Summary:

Reviewed studies include drug resistance analysis, early diagnostic techniques, neuropathy mechanisms, Mycobacterium leprae growth, molecular epidemiology, new drug discovery, vaccine development, and in vitro cultivation.
Proposed future studies focus on relapse mechanisms, reaction diagnostics and prevention, and immunological mechanisms of anergy in lepromatous leprosy (LL) cases.
Discussion centered on future collaborative efforts between Japan and Korea to address remaining challenges in clinical leprosy management.

Impact:

Advances in understanding leprosy pathogenesis and treatment.
Potential for improved diagnostic tools and therapeutic strategies.
Strengthened international research cooperation for leprosy elimination.