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Ferric Chloride-induced Canine Carotid Artery Thrombosis: A Large Animal Model of Vascular Injury
Published on: September 7, 2018
Aortic thrombosis in dogs: 31 cases (2000-2010)
Geri A Lake-Bakaar1, Eric G Johnson, Leigh G Griffiths
1Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, 95616, USA.
Journal of the American Veterinary Medical Association
|September 28, 2012
Summary
Aortic thrombosis in dogs is rare, with clinical signs varying by onset. Chronic cases had longer survival than acute ones, though outcomes were generally poor.
Area of Science:
- Veterinary Medicine
- Cardiovascular Pathology
- Canine Health
Background:
- Aortic thrombosis is a serious condition in dogs.
- Understanding its clinical presentation and outcomes is crucial for veterinary care.
- This study investigates aortic thrombosis in a canine population.
Purpose of the Study:
- To detail the clinical signs, treatment strategies, and survival outcomes for dogs diagnosed with aortic thrombosis.
- To differentiate canine aortic thrombosis from feline aortic thromboembolism.
- To analyze factors influencing survival time, such as disease onset.
Main Methods:
- A retrospective case series design was employed.
- Data from 31 dogs diagnosed with aortic thrombosis (clinically or postmortem) were reviewed.
- Information collected included signalment, clinical signs, physical examination findings, laboratory results, and concurrent diseases.
Main Results:
- Clinical signs varied in onset (acute in 45%, chronic in 48%).
- Physical exam findings included weak or absent femoral pulses (74%).
- Common lab abnormalities included elevated BUN, creatinine, CK, D-dimer, and proteinuria. Median survival was significantly longer for chronic (30 days) versus acute (1.5 days) onset.
Conclusions:
- Aortic thrombosis is a rare condition in dogs, representing 0.0005% of hospital admissions.
- Clinical signs in dogs differ from feline aortic thromboembolism.
- While outcomes are typically poor despite treatment, chronic disease onset is associated with longer survival.
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