Related Experiment Video
Updated: May 18, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
Radioiodine therapy of metastatic lesions of differentiated thyroid cancer
M Luster1, H Hänscheid, L S Freudenberg
1Department of Nuclear Medicine, University of Ulm, Albert-Einstein-Allee 23, Ulm, Germany. markus.luster@uniklinik-ulm.de
Abstract:
Seventy years after the first successful radioiodine treatment of metastatic differentiated thyroid cancer (DTC), radioiodine (131I) therapy for this type of tumor is still without alternative. During the last decade, some key issues such as individual dosimetry, and preparation of 131I therapy by recombinant human TSH have been addressed, but this has not yet lead to conclusive results; furthermore a number of questions related to indication, preparation, and treatment protocol of 131I therapy still remain unanswered. In this review, we will address the literature pertaining to the latest developments in the field of 131I therapy of advanced DTC and we will give an overview of the state of the art regarding patient preparation, dosimetry, and therapy.
Related Concept Videos
Goiter
Graves Disease II: Pathophysiology
Hyperthyroidism I: Introduction
Synthesis and Regulation of Thyroid Hormones
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The iodine is then...
Hyperthyroidism II: Pathophysiology
Graves' Disease I: Introduction

