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High Throughput, Real-time, Dual-readout Testing of Intracellular Antimicrobial Activity and Eukaryotic Cell Cytotoxicity
Published on: November 16, 2016
Cell culture assays to evaluate bacterial toxicity and virulence
Deepa Raju1, David Rizzuti, Nicola L Jones
1Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto, ON, Canada.
Methods in Molecular Biology (Clifton, N.J.)
|September 28, 2012
Abstract:
Helicobacter pylori CagA and VacA are two critical virulence factors that modulate disease severity in the infected host. The following chapter outlines methods employed to study the effects of these virulence factors on several key signaling pathways in epithelial cells.
