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Related Experiment Video

Updated: May 18, 2026

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties
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Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties

Published on: May 10, 2018

Development of silver nanoparticle loaded antibacterial polymer mesh using plasma polymerization process.

Virendra Kumar1, Claude Jolivalt, Jerome Pulpytel

  • 1Laboratoire de Génie des Procédés Plasmas et Traitement de Surface, Université Pierre et Marie Curie, ENSCP-Chimie Paris Tech, Paris, France. vkrawat75@gmail.com

Journal of Biomedical Materials Research. Part A
|September 28, 2012
PubMed
Summary

Plasma polymerized polyacrylic acid (PPAA) coatings on polyethylene terephthalate (PET) mesh effectively entrap silver nanoparticles (Ag-NPs). This novel material demonstrates over 99% antibacterial reduction against common bacteria.

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Biomedical Engineering

Background:

  • Polymer substrates require functionalization for advanced applications.
  • Silver nanoparticles (Ag-NPs) possess inherent antimicrobial properties.
  • Developing effective methods for Ag-NP immobilization is crucial for antibacterial materials.

Purpose of the Study:

  • To develop an antibacterial polyethylene terephthalate (PET) mesh.
  • To functionalize PET mesh with plasma polymerized polyacrylic acid (PPAA) for Ag-NP entrapment.
  • To characterize the Ag-NP loaded PPAA-PET mesh and evaluate its antibacterial efficacy.

Main Methods:

  • Plasma polymerization of PPAA onto PET mesh.
  • Chemical synthesis and stabilization of Ag-NPs using PPAA.
  • Characterization using FTIR, XPS, water contact angle, UV-Vis, FESEM, and EDX.
  • Antibacterial testing against Staphylococcus aureus and Escherichia coli.

Main Results:

  • PPAA coatings were successfully characterized on PET mesh.
  • XPS confirmed ~1.0 at.% Ag-NP loading, with 79% zero-valent Ag.
  • The Ag-NP loaded PPAA-PET mesh exhibited >99% bacterial reduction against both Gram-positive and Gram-negative bacteria.

Conclusions:

  • Plasma polymerized polyacrylic acid serves as an effective platform for anchoring and stabilizing Ag-NPs on PET mesh.
  • The developed Ag-NP-functionalized PPAA-PET mesh demonstrates significant and broad-spectrum antibacterial activity.
  • This material holds promise for applications requiring antimicrobial surfaces.