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Cancer

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

Cancer Vaccines

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...

Adaptive Mechanisms in Cancer Cells

Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...

Adaptive Mechanisms in Cancer Cells

Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...

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Related Experiment Video

Updated: May 18, 2026

A Streamlined Approach for Mass Spectrometry-Based Proteomics Using Selected Tissue Regions

A Streamlined Approach for Mass Spectrometry-Based Proteomics Using Selected Tissue Regions

Published on: April 18, 2025

Anticancer peptides and proteins: a panoramic view.

M S Libério¹, G A Joanitti, W Fontes

¹Toxinology Laboratory, Department of Physiological Sciences, Institute of Biology, University of Brasilia, Brasilia/DF, Brazil, 70910-900.

Protein and Peptide Letters

|September 29, 2012

Summary

This summary is machine-generated.

Antimicrobial peptides (AMPs) offer a novel strategy against cancer, overcoming treatment resistance mechanisms like DNA repair and apoptosis evasion. These biologically active peptides show promise in developing new cancer therapies.

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Area of Science:

Oncology
Biochemistry
Molecular Biology

Background:

Cancer remains a leading global cause of death despite advances in understanding carcinogenesis.
Tumor resistance to chemotherapy is a major challenge, stemming from DNA repair, altered drug interactions, and apoptosis defects.

Purpose of the Study:

To explore novel therapeutic strategies for cancer treatment.
To investigate the potential of biologically active peptides, particularly antimicrobial peptides (AMPs), in combating cancer.

Main Methods:

Review of existing literature on cancer treatment resistance mechanisms.
Analysis of the properties and mechanisms of action of antimicrobial peptides (AMPs).
Exploration of peptide- and protein-based therapies in preclinical and clinical settings.

Main Results:

Antimicrobial peptides (AMPs) demonstrate potent anticancer activities.
AMPs can overcome common cancer drug resistance mechanisms.
Peptide- and protein-based therapies represent a promising new avenue for cancer treatment.

Conclusions:

Antimicrobial peptides (AMPs) present a viable and novel therapeutic approach for cancer.
Targeting cancer with AMPs could overcome limitations of current chemotherapeutics.
Further research into AMPs and proteins is crucial for developing next-generation cancer treatments.