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Updated: May 18, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
Early onset sepsis in very low birth weight newborn infants
Valentina Pisani1, Bianca Bizzarri, Veronica Cardi
1Paediatrics and Infant Neuropsychiatry Department, Sapienza University of Rome, Rome, Italy.
Abstract:
Early onset sepsis (EOS) is a severe problem affecting very low birth weight (VLBW) infants and is associated with a threefold increased risk of mortality. Although advances in perinatal care have led to improved survival of VLBW infants over recent decades, survival without major neonatal morbidity has not increased. The authors reviewed the current literature on EOS, focusing on the peculiarities concerning risk factors, etiology, diagnosis, treatment and outcome in very low birth weight infants, and on the recent advances in the management of this condition.
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