Related Experiment Video
Updated: May 18, 2026

Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration
Published on: April 4, 2022
Stable angina pectoris: current medical treatment
Katerina Siama1, Dimitris Tousoulis, Nikolaos Papageorgiou
11st Cardiology Unit, Hippokration Hospital, Athens University Medical School, Greece.
Stable angina management focuses on symptom relief and secondary prevention for coronary artery disease. Optimal medical therapy combines traditional drugs with newer agents like ranolazine, whose long-term effects require further study.
Area of Science:
- Cardiology
- Pharmacology
Background:
- Stable angina is a primary symptom of coronary artery disease (CAD), with atherosclerosis as the underlying pathology.
- CAD management involves lifestyle changes, pharmacotherapy, and potentially revascularization procedures.
Purpose of the Study:
- To outline the aims of stable angina management, emphasizing symptomatic relief and secondary prevention.
- To review current pharmacological strategies for chronic CAD, including established and novel treatments.
Main Methods:
- Review of established medical therapies for CAD, including nitrates, beta-blockers, calcium channel blockers, antiplatelets, statins, and ACE inhibitors.
- Identification and discussion of novel antianginal drug classes such as nicorandil, ivabradine, trimetazidine, and ranolazine.
Main Results:
- Optimal medical therapy integrates antianginal/anti-ischemic drugs with disease-modifying agents.
- Newer drug classes are increasingly used as second-line treatments for stable angina.
Conclusions:
- Comprehensive management of chronic stable angina relies on lifestyle modifications and optimal medical therapy.
- Emerging treatments offer alternative mechanisms of action, but their long-term efficacy and safety profiles are under ongoing investigation.
More Related Videos
18:11A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
Published on: December 28, 2012
06:39Intracoronary Acetylcholine Provocation Testing for Assessment of Coronary Vasomotor Disorders
Published on: August 18, 2016
Related Concept Videos
Angina IV: Management
Angina V: Nursing Management
Angina II: Classification
Angina III: Clinical Manifestations and Assessment
Acute Coronary Syndrome IV: Interprofessional Care
Coronary Artery Disease V: Interprofessional Care