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Related Experiment Video

Updated: Jan 20, 2026

Behavioral Tests to Assess Executive Functions in Children with ASD
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Correlations between executive function, decision-making and impulsivity are disrupted in schizophrenia versus

Victoria Caroline Wing1, Rachel Allison Rabin, Caroline Emma Wass

  • 1Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, Canada. vicky.wing@camh.ca

Psychiatry Research
|September 29, 2012
PubMed
Summary

Executive function and decision-making are linked in healthy individuals but not in schizophrenia patients, even when matched for smoking history. This suggests a breakdown in cognitive integration in schizophrenia.

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Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Psychiatry

Background:

  • Schizophrenia is a complex mental disorder affecting cognition.
  • Executive function, decision-making, and impulsivity are key cognitive domains.
  • Understanding cognitive deficits in schizophrenia is crucial for treatment.

Purpose of the Study:

  • To investigate the relationships between executive function, decision-making, and impulsivity in schizophrenia.
  • To compare these relationships in schizophrenia patients and matched controls.
  • To explore potential cognitive integration deficits in schizophrenia.

Main Methods:

  • Assessed 68 schizophrenia patients and 62 control participants.
  • Participants were matched for cigarette smoking history.
  • Utilized executive function, decision-making, and impulsivity tasks.

Main Results:

  • In controls, executive function and decision-making showed positive correlations.
  • Impulsivity was negatively correlated with executive function and decision-making in controls.
  • No significant inter-task correlations were observed in schizophrenia participants.

Conclusions:

  • Schizophrenia disrupts the integration between executive function, decision-making, and impulsivity.
  • These findings highlight distinct cognitive processing in schizophrenia compared to controls.
  • Further research is needed to understand the implications for schizophrenia pathophysiology and treatment.