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Relaxin-3 is associated with metabolic syndrome and its component traits in women
Maivel H Ghattas1, Eman T Mehanna, Noha M Mesbah
1Department of Medical Biochemistry, Faculty of Medicine, Suez Canal University, 41522 Ismailia, Egypt.
Objectives:
Relaxin-3 was found to play a role in appetite regulation, increasing food intake and body weight. The current study aimed to investigate the relation of relaxin-3 to metabolic syndrome and its component traits in women.
Design And Methods:
The study was conducted on 300 female subjects, 150 healthy control and 150 metabolic syndrome patients. The component traits of metabolic syndrome were determined for all participants.
Results:
Serum relaxin-3 level was significantly higher in the metabolic syndrome patients than in the healthy control group. It was also significantly correlated with all the component traits of metabolic syndrome.
Conclusion:
The results suggest that metabolic syndrome is associated with increased serum relaxin-3 levels in women. Relaxin-3 might be considered as a potential biomarker of metabolic syndrome.
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