Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hyperthyroidism II: Pathophysiology01:27

Hyperthyroidism II: Pathophysiology

Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...
The Parathyroid Glands00:59

The Parathyroid Glands

The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by producing...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Hypothyroidism II: Pathophysiology01:23

Hypothyroidism II: Pathophysiology

Hypothyroidism is a disorder characterized by insufficient production of thyroid hormones, which regulate metabolism, energy balance, and multiple organ systems.TypesHypothyroidism is classified based on the level of dysfunction. Primary hypothyroidism results from intrinsic thyroid gland dysfunction, causing reduced hormone production despite normal or increased stimulation. Secondary hypothyroidism arises from inadequate thyroid-stimulating hormone (TSH) secretion by the pituitary. Tertiary...
Hyperthyroidism I: Introduction01:25

Hyperthyroidism I: Introduction

Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Primary melanoma of the gastrointestinal tract.

World journal of gastroenterology·2026
Same author

A viable human lung cancer tissue collection (LCTC) to accelerate translational research.

Cancer treatment and research communications·2026
Same author

Impact of platinum-based chemotherapy and CTLA-4 inhibition on acquired resistance to first-line anti-PD-1/PD-L1 agents in non-small cell lung cancer: a systematic review and reconstructed individual patient data analysis.

EClinicalMedicine·2025
Same author

Biliary Injuries Repair Using Copolymeric Scaffold: A Systematic Review and In Vivo Experimental Study.

Journal of functional biomaterials·2025
Same author

Potential Applications of PRP-Enhanced Polybutylene Succinate Graft as Vascular Access for Chemotherapy in Oncological Patients: A Systematic Review.

Journal of functional biomaterials·2025
Same author

Skin Photodamage and Melanomagenesis: A Comprehensive Review.

Cancers·2025

Related Experiment Video

Updated: May 18, 2026

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

Post-transplantation tertiary hyperparathyroidism.

Maria Concetta Gioviale1, Maurizio Bellavia, Giuseppe Damiano

  • 1Department of Surgical and Oncological Disciplines, Università degli Studi di Palermo, Viadel Vespro 129, Palermo, Italy.

Annals of Transplantation
|September 29, 2012
PubMed
Summary

Tertiary hyperparathyroidism involves excessive parathyroid hormone after secondary hyperparathyroidism, persisting post-kidney transplant and worsening graft function. Management strategies are reviewed for transplant candidates.

More Related Videos

Procurement of Parathyroid Glands from Living Donor Pigs and Ex Vivo Identification
08:07

Procurement of Parathyroid Glands from Living Donor Pigs and Ex Vivo Identification

Published on: August 1, 2025

Related Experiment Videos

Last Updated: May 18, 2026

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

Procurement of Parathyroid Glands from Living Donor Pigs and Ex Vivo Identification
08:07

Procurement of Parathyroid Glands from Living Donor Pigs and Ex Vivo Identification

Published on: August 1, 2025

Area of Science:

  • Nephrology
  • Endocrinology
  • Transplantation

Background:

  • Tertiary hyperparathyroidism (THP) is autonomous parathyroid hormone (PTH) overproduction.
  • It follows prolonged secondary hyperparathyroidism, often in chronic kidney disease.
  • THP can persist after successful kidney transplantation, impacting graft outcomes.

Purpose of the Study:

  • To review the pathogenesis, prevention, and treatment of tertiary hyperparathyroidism.
  • To discuss the clinical implications of persistent hyperparathyroidism after renal transplantation.
  • To provide guidance on managing patients awaiting kidney transplantation.

Main Methods:

  • Literature review of tertiary hyperparathyroidism.
  • Analysis of pathogenesis, clinical presentation, and management strategies.
  • Synthesis of current evidence on prevention and treatment.

Main Results:

  • Persistent high PTH levels in renal recipients impair graft function and cause systemic symptoms.
  • Understanding pathogenesis is key to developing targeted prevention and treatment.
  • Management requires a multifaceted approach, including pre-transplant optimization.

Conclusions:

  • Tertiary hyperparathyroidism poses a significant challenge in kidney transplant recipients.
  • Early identification and management are crucial for improving graft survival and patient well-being.
  • Optimizing care for patients on the transplant waiting list may mitigate THP development.