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Related Concept Videos

Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
Schizophrenia01:17

Schizophrenia

Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

Positive Symptoms Schizophrenia: Hallucinations and Delusions

Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic symptoms in all...

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Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
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Published on: September 8, 2021

Schizophrenia and suicide.

Y Ps Balhara1, R Verma

  • 1National Drug Dependence Treatment Centre, All India Institute of Medical Sciences, New Delhi, India.

East Asian Archives of Psychiatry : Official Journal of the Hong Kong College of Psychiatrists = Dong Ya Jing Shen Ke Xue Zhi : Xianggang Jing Shen Ke Yi Xue Yuan Qi Kan
|September 29, 2012
PubMed
Summary
This summary is machine-generated.

Schizophrenia significantly increases suicide risk, with male gender, unmarried status, depression, and illness insight being key factors. Further research is needed on interventions for suicide prevention in schizophrenia patients.

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A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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Last Updated: May 18, 2026

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
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A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
05:51

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

Published on: June 15, 2011

Area of Science:

  • Psychiatry
  • Mental Health Research
  • Epidemiology

Background:

  • Schizophrenia is a chronic mental disorder characterized by distorted thinking and perception.
  • Suicide is a major global health concern, accounting for nearly 2% of world deaths.
  • A significant association exists between schizophrenia and increased suicide risk, leading to personal distress and reduced life expectancy.

Purpose of the Study:

  • To review the current literature on suicide in schizophrenia.
  • To identify key risk factors and epidemiological findings related to suicide in schizophrenia patients.
  • To explore the relationship between schizophrenia, its symptoms, and suicidal behavior.

Main Methods:

  • A comprehensive literature search was conducted across multiple databases: MEDLINE, CINHAL, EMBASE, and Cochrane Controlled Trials Register.
  • Search terms included 'schizophrenia', 'suicide', 'positive symptoms', 'negative symptoms', 'self-harm', 'anti-psychotics', and 'risk factors'.
  • Data extraction included epidemiological, socio-demographical, symptomatic, biological, risk factor, and management information from English-language articles.

Main Results:

  • Male gender and being unmarried are associated with a higher risk of suicide in individuals with schizophrenia.
  • The presence of depression and depressive symptoms significantly increases suicidality risk.
  • Greater insight into the illness, leading to hopelessness, is consistently linked to an elevated suicide risk, though schizophrenia subtype's role remains debated.

Conclusions:

  • Established risk factors for suicide in schizophrenia include male gender, unmarried status, depression, and illness insight.
  • The effectiveness of specific pharmacological and non-pharmacological interventions on suicidal behavior in schizophrenia requires further investigation through robust research.