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Updated: May 18, 2026

Fiber Connections of the Supplementary Motor Area Revisited: Methodology of Fiber Dissection, DTI, and Three Dimensional Documentation
Published on: May 23, 2017
Comment on "The geometric structure of the brain fiber pathways"
Marco Catani1, Istvan Bodi, Flavio Dell'Acqua
1NATBRAINLAB, Department of Neuroimaging, Institute of Psychiatry, King's College London, London, UK. m.catani@iop.kcl.ac.uk
Abstract:
Wedeen et al. (Reports, 30 March 2012, p. 1628) proposed a geometrical grid pattern in the brain that could help the understanding of the brain's organization and connectivity. We show that whole-brain fiber crossing quantification does not support their theory. Our results suggest that the grid pattern is most likely an artifact attributable to the limitations of their method.
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