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Updated: May 18, 2026
An In Vitro Dissolution Determination of Multi-Index Components in Tibetan Medicine Rhodiola Granules
Published on: November 4, 2022
[Chemical constituents contained in Macropanax rosthornii]
Yongming Luo1, Hua Liu, Xiaoying Yin
1Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China. loym999@163.com
Objective:
To study active constituents of Macropanax rosthornii in treating rheumatoid arthritis.
Method:
Silica gel column chromatography, preparative HPLC and modern spectrum techniques were applied for a systematic study on chemical constituents contained in M. rosthornii.
Result:
Twelve compounds were separated from M. rosthornii and identified as serratagenic acid (1), serjanic acid (2), betulinic acid (3), 6beta-hydroxy-3-oxo-olean-12-en-28-oic acid (4), 3-O-alpha-L-arabinopyranosyl serratagenic acid (5), 3-O-alpha-L-arabinopyranosyl serratagenic acid-29-methyl ester (6) , 3-O-alpha-L-arabinopyranosyl serratagenic acid-28-O-beta-D-glucopyranosyl ester (7), scopoletin (8), beta-sitosterol (9), daucosterol (10), 3,4-dihydroxybenzoic acid (11), and stearic acid (12).
Conclusion:
Above compounds are separated from M. rosthornii for the first time.
