[Cardiorenal syndrome: currents views of relationships between renal and cardiovascular diseases]

Area of Science:

• Nephrology
• Cardiology
• Pathophysiology

Context:

• Cardiorenal syndrome involves complex interactions between the heart and kidneys.
• Chronic renal diseases (CRD) are increasingly recognized as significant risk factors for cardiovascular disorders (CVD).
• Understanding these interconnections is crucial for managing patients with co-existing heart and kidney conditions.

Purpose:

• To review current concepts on the development and pathogenesis of cardiorenal syndrome.
• To emphasize the role of CRD as a risk factor for CVD.
• To explore the pathophysiological features linking CRD and CVD.

Summary:

• The pathogenesis of cardiorenal syndrome is examined, focusing on chronic renal diseases as cardiovascular risk factors.
• Pathophysiological mechanisms underlying cardiovascular disorders concurrent with chronic renal diseases are detailed.
• The relationship between chronic renal diseases and established cardiovascular risk factors is elucidated.
• Renal dysfunction is presented as a potential complication arising from heart failure, underscoring the syndrome's complexity.

Impact:

• Provides a comprehensive overview of cardiorenal syndrome, aiding clinical understanding.
• Highlights the critical link between kidney health and cardiovascular outcomes.
• Informs strategies for managing patients with cardiorenal conditions and associated risk factors.