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Multifocal meningioangiomatosis in a 3-year-old patient
Osama Jamil1, Shakti Ramkissoon, Rebecca Folkerth
1Department of Neurosurgery, Children’s Hospital Boston, 300 Longwood Avenue,Boston, Massachusetts 02115, USA.
Abstract:
Meningioangiomatosis consists of benign hamartomatous lesions of the brain and the leptomeninges, which typically present with seizure. Management is predicated on resection and control of seizures with medication. Lesions are typically solitary. Multifocal meningioangiomatosis is extremely rare, with only 2 cases reported in adults and none in children. The authors report the first case, to their knowledge, of multifocal meningioangiomatosis in a child. This unique case highlights therapeutic challenges associated with these lesions and demonstrates that multifocality is possible in the pediatric population. This finding has implications for diagnosis and follow-up for children afflicted with these tumors.
Insights
Multifocal meningioangiomatosis, a rare brain and leptomeninges tumor, is reported for the first time in a child. This rare pediatric case highlights diagnostic and therapeutic challenges of these benign hamartomatous lesions.
Area of Science:
- Neurology
- Pediatric Oncology
- Neurosurgery
Background:
- Meningioangiomatosis comprises benign hamartomatous lesions affecting the brain and leptomeninges.
- Typically presenting with seizures, management involves surgical resection and anticonvulsant medication.
- These lesions are usually solitary, with multifocal presentations being exceptionally rare.
Observation:
- The authors present the first documented case of multifocal meningioangiomatosis in a pediatric patient.
- This unique case underscores the potential for multifocal development in children, previously unreported.
- The patient's presentation and management highlight specific challenges in pediatric cases.
Findings:
- Multifocal meningioangiomatosis can occur in children, contrary to previous reports.
- This case confirms the possibility of multiple lesions in pediatric meningioangiomatosis.
- The benign, hamartomatous nature of the lesions was confirmed.
Implications:
- This finding expands the understanding of meningioangiomatosis presentation in pediatric populations.
- It necessitates consideration of multifocal disease in the diagnosis and follow-up of children with these tumors.
- Improved diagnostic strategies and long-term monitoring protocols may be required for affected children.
