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General anesthesia for intussusception reduction by enema
Emilien Purenne1, Stéphanie Franchi-Abella, Sophie Branchereau
1Département d'Anesthésie-Réanimation, Hôpitaux Universitaires Paris-Sud, Assistance Publique - Hôpitaux de Paris, Paris, France.
Insights
General anesthesia (GA) significantly increases the success rate of air enema for pediatric intussusception reduction. This approach achieves over 90% success, improving outcomes for bowel obstruction treatment.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Medical Imaging
Background:
- Intussusception is a leading cause of bowel obstruction in children.
- Enema is the primary treatment, but over 50% may require surgery.
- General anesthesia (GA) is hypothesized to improve enema success rates.
Purpose of the Study:
- To determine if GA enhances the success rate of air enema for intussusception reduction.
- To compare air enema success rates between patients receiving sedation versus GA.
Main Methods:
- Retrospective single-center study (1989-2008).
- Analysis of patients undergoing air enema for intussusception.
- Propensity score matching for multivariable analysis comparing sedation and GA groups.
Main Results:
- Overall air enema success rate improved from 72% to 90%.
- Delayed treatment (>12 hours) significantly decreased success rates (OR 0.67).
- GA significantly increased success likelihood (OR 5.66) after propensity score matching.
Conclusions:
- Air enema under GA achieves over 90% success in reducing intussusception.
- GA is a valuable tool for improving non-surgical reduction rates.
- Timely intervention remains critical for successful enema treatment.
Objectives:
Intussusception is the most frequent cause of bowel obstruction in children. Although enema is usually used as the initial treatment, surgery may be required in more than 50% of patients. General anesthesia (GA) has been suggested to increase the rate of enema success. The purpose of this study was to evaluate whether GA increases the success rate of reduction by air enema.
Methods:
In this retrospective single-center study from 1989 to the end of June 2008, patients receiving air enema for intussusception reduction were studied. Multivariable analysis using propensity score was performed to compare the success rate between patients receiving sedation or GA.
Results:
The success rate of air enema increased from 72% in 1989 to the current rate of 90%. When time elapsed between first symptoms and enema was >12 h, the success rate decreased significantly (Odds Ratio 0.67 [0.56-0.81], P < 0.0001). When patients were matched by propensity score, GA significantly increased the likelihood of success (OR 5.66 [2.85-12.89], P = 0.013).
Conclusions:
Air enema performed under GA allows intussusception reduction in more than 90% of patients.
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