Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Familial hemifacial spasm.

J B Carter1, J R Patrinely, J Jankovic

  • 1Department of Ophthalmology, Cullen Eye Institute, Houston, Tex.

Archives of Ophthalmology (Chicago, Ill. : 1960)
|February 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biliary Enterocytozoon bieneusi infection in a dog under immunomodulatory therapy.

The Journal of small animal practice·2023
Same author

Hyperkinetic movement disorders in congenital disorders of glycosylation.

European journal of neurology·2019
Same author

McLeod syndrome: Five new pedigrees with novel mutations.

Parkinsonism & related disorders·2019
Same author

Hemocytes and granular cell fragments of Tipula paludosa larvae.

Journal of morphology·2018
Same author

Association between non-communicable disease multimorbidity and health care utilization in a middle-income country: population-based study.

Public health·2018
Same author

Treatment options for chorea.

Expert review of neurotherapeutics·2017
Same journal

The economics of the initial preventive physical examination in medicare-reply.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

Modification of silicone oil retention sutures in aphakic eyes with iris loss-reply;.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

December 2011 archives web quiz winner.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

Angle involvement and glaucoma in patients with biopsy-proven iris melanoma: a response-reply.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

About this journal.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

In memoriam: goodwin m. Breinin, MD (1918-2011).

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
See all related articles

This study identifies a potential genetic link in hemifacial spasm, suggesting an autosomal dominant inheritance pattern. Familial cases may present with earlier onset and consistent facial side involvement.

Area of Science:

  • Neurology
  • Genetics
  • Neuroanatomy

Background:

  • Hemifacial spasm (HFS) is an involuntary movement disorder affecting facial muscles.
  • While often idiopathic or secondary to vascular compression, familial cases are increasingly recognized.

Observation:

  • Three male patients across successive generations of a single family presented with acquired left-sided hemifacial spasm.
  • The proband's MRI revealed a pontine vertebral artery anomaly adjacent to the facial nerve root.

Findings:

  • Hemifacial spasm may exhibit autosomal dominant inheritance.
  • Facial involvement in familial HFS is consistently ipsilateral (same side) within a family.
  • Familial cases of hemifacial spasm can have a younger age of onset compared to non-familial cases.

Related Experiment Videos

Implications:

  • This suggests a potential genetic predisposition and etiology for certain hemifacial spasm cases.
  • Understanding familial patterns aids in diagnosis and genetic counseling for hemifacial spasm.
  • Further research into vascular anomalies and genetic factors in HFS is warranted.