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Updated: May 18, 2026
07:26
Ferric Chloride-induced Thrombosis Mouse Model on Carotid Artery and Mesentery Vessel
Published on: June 29, 2015
[Evaluation for antithrombotic agents by a thrombotic model in animals]
1Department of Pharmacology, Hamamatsu University School of Medicine, Shizuoka, Japan. yapplel@hama-med.ac.jp
Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan
|October 2, 2012
Summary
Microplasmin reduced brain damage and neurological deficits in an animal stroke model. The study identified the tissue-type plasminogen activator/low-density lipoprotein receptor-related protein/matrix metalloproteinase-3 pathway as a target to mitigate intracranial hemorrhage risk.
Area of Science:
- Neuroscience
- Biochemistry
- Pharmacology
