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Updated: May 18, 2026

A Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria
Published on: June 27, 2022
A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells
1Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai, 200237, China.
Abstract:
A new ratiometric fluorescence probe E1 based on an excited-state intramolecular proton transfer (ESIPT) mechanism for detection of hydrogen sulfide (H(2)S) is reported. E1 responds to H(2)S quickly and showed a 30-fold fluorescence enhancement in 2 minutes. Moreover, E1 can detect H(2)S quantitatively with a detection limit as low as 0.12 μM in aqueous solution. Its potential for biological applications was confirmed by employing it for fluorescence imaging of H(2)S in living cells.
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