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Introduction to Electrolytes

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In humans, electrolytes play a vital role in various physiological processes. Balancing electrolyte levels is essential for normal body functions; their imbalance can be life-threatening. The major electrolytes include sodium, potassium, chloride, calcium, phosphate, and bicarbonate. They are primarily involved in physiological processes, such as nerve signal transmission, membrane trafficking, muscle contraction, buffering body fluids, and balancing water levels in the body.
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Related Experiment Video

Updated: May 18, 2026

Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry

Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry

Published on: July 26, 2019

[Phosphate sensing and intestine].

Sawako Tatsumi¹, Kengo Nomura, Atsumi Miyagawa

¹Department of Molecular Nutrition, Institution of Health Biosciences, The University of Tokushima Graduate School, Japan.

Clinical Calcium

|October 2, 2012

Summary

The small intestine senses nutrients, including dietary phosphate. Understanding this mechanism could help prevent hyperphosphatemia in chronic kidney disease patients.

Area of Science:

Gastroenterology and Nephrology
Nutrient Sensing Mechanisms

Context:

The small intestine is crucial for nutrient sensing.
Emerging evidence suggests a dietary phosphate sensing mechanism in the intestine.
Intestinal factors may influence renal phosphate transport.

Purpose:

To elucidate the molecular mechanisms of intestinal phosphate sensing.
To understand the link between intestinal phosphate sensing and renal phosphate regulation.

Summary:

Investigates the role of the small intestine in dietary phosphate sensing.
Explores how intestinal phosphate sensing might alter renal phosphate transport.
Identifies potential molecular targets for managing phosphate homeostasis.

Impact:

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Optical Quantification of Intracellular pH in Drosophila melanogaster Malpighian Tubule Epithelia with a Fluorescent Genetically-encoded pH Indicator

Optical Quantification of Intracellular pH in Drosophila melanogaster Malpighian Tubule Epithelia with a Fluorescent Genetically-encoded pH Indicator

Published on: August 11, 2017

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Last Updated: May 18, 2026

Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry

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Published on: July 26, 2019

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor

Published on: February 10, 2014

Optical Quantification of Intracellular pH in Drosophila melanogaster Malpighian Tubule Epithelia with a Fluorescent Genetically-encoded pH Indicator

Optical Quantification of Intracellular pH in Drosophila melanogaster Malpighian Tubule Epithelia with a Fluorescent Genetically-encoded pH Indicator

Published on: August 11, 2017

Provides a molecular basis for preventing hyperphosphatemia.
Offers insights into therapeutic strategies for chronic kidney disease patients.
Enhances understanding of nutrient-sensing pathways and their systemic effects.