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Encapsulation of biomacromolecules within polymersomes by electroporation
Linge Wang1, Luca Chierico, Daniel Little
1The Krebs Institute, UK.
Angewandte Chemie (International Ed. in English)
|October 2, 2012
Abstract:
Biological macromolecules can be encapsulated into preformed polymersomes by controlled temporary destabilization of the vesicle membrane. The morphology and the size of the polymersome are unchanged after electroporation, suggesting that the polymersome membrane is reformed. The surface charge of the biomacromolecules plays a key role for the electroporation process.
