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Related Experiment Video

Updated: May 18, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

New daily persistent headache.

¹West of Scotland Regional Headache Service, Department of Neurology, Institute of Neurological Sciences, Southern General Hospital, Glasgow, United Kingdom.

Annals of Indian Academy of Neurology

|October 2, 2012

Summary

This summary is machine-generated.

New daily persistent headache (NDPH) is a syndrome characterized by acute onset headaches. Many NDPH cases exhibit migrainous features, necessitating migraine-targeted treatments.

Keywords:

Chronic daily headache intractable headache new daily persistent headache

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Area of Science:

Neurology
Headache Medicine

Background:

New daily persistent headache (NDPH) is a distinct primary headache disorder.
It is characterized by a rapid onset, reaching peak intensity within three days.
NDPH requires differentiation from secondary causes, especially those related to cerebrospinal fluid (CSF) pressure.
The syndrome can mimic chronic migraine and tension-type headaches.

Purpose of the Study:

To define the characteristics of NDPH.
To emphasize the importance of excluding secondary headache causes.
To guide appropriate management strategies for NDPH patients.

Main Methods:

Literature review of NDPH characteristics and diagnostic criteria.
Analysis of clinical features and treatment responses in NDPH cohorts.
Differential diagnosis considerations, including CSF pressure abnormalities.

Main Results:

NDPH presents as a new-onset chronic headache syndrome.
A significant subset of NDPH patients exhibit migrainous features.
Some NDPH cases are refractory to standard treatments, indicating intractability.

Conclusions:

NDPH should be considered a syndrome, not a definitive diagnosis.
Management should include ruling out secondary causes and addressing migrainous features.
Treatment strategies often align with those for chronic migraine, with a subset requiring specialized care for intractable pain.