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Overview of resistant hypertension: A glimpse of the cardiologist's current standpoint
Luis Paiva1, Maria Carmo Cachulo, Rui Providencia
1Luis Paiva, Maria Carmo Cachulo, Rui Providencia, Sergio Barra, Paulo Dinis, Antonio Leitao-Marques, Cardiology Department, Coimbra's Hospital and University Centre, 3041-801 Coimbra, Portugal.
Insights
Uncontrolled hypertension, especially resistant hypertension, poses significant cardiovascular risks despite available treatments. Recent research improves understanding of this complex condition and its management.
Area of Science:
- Cardiology
- Nephrology
- Public Health
Background:
- Hypertension is a primary risk factor for cardiovascular disease, leading to cerebrovascular events, ischemic heart disease, heart failure, and renal impairment.
- It is a leading preventable cause of premature death and disability.
- Despite effective treatments, uncontrolled hypertension persists as a clinical challenge.
Purpose of the Study:
- To provide an overview of resistant hypertension.
- To highlight recent advancements in understanding and managing resistant hypertension.
Main Methods:
- Literature review of recent publications on resistant hypertension.
- Synthesis of current knowledge on contributing factors and comorbidities.
Main Results:
- Resistant hypertension is a complex condition influenced by multiple factors and comorbidities.
- Recent studies have enhanced the understanding of its pathophysiology and clinical implications.
Conclusions:
- Further research is needed to establish evidence-based guidelines for resistant hypertension.
- Improved understanding facilitates better management strategies for patients with resistant hypertension.
Abstract:
Hypertension is a major risk factor for cardiovascular disease, resulting in increased incidence of cerebrovascular events, ischaemic heart disease, heart failure, and renal impairment. Thus, it is one of the most important preventable causes of premature morbidity and mortality. Despite current knowledge on the management of hypertension and the availability of several effective antihypertensive medications, uncontrolled hypertension remains a common and challenging clinical problem. Resistant hypertension is a complex condition with multiple contributing factors and overlapping comorbidities. Although there is limited hard evidence regarding resistant hypertension, our understanding of this condition has improved recently. This article will present an overview of resistant hypertension and highlight recent publications about this topic.
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