Endovascular treatment of extracranial vertebral artery stenosis

Burak Kocak1, Bora Korkmazer, Civan Islak

  • 1Burak Kocak, Bora Korkmazer, Civan Islak, Naci Kocer, Osman Kizilkilic, Department of Radiology, Division of Neuroradiology, Cerrahpasa School of Medicine, Istanbul University, 34098 Istanbul, Turkey.

Insights

Percutaneous angioplasty and stenting for vertebral artery stenosis is a feasible treatment. However, more randomized trials are needed to prove its superiority over medical management.

Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Neurology

Background:

  • Extracranial vertebral artery (VA) stenosis can cause posterior circulation symptoms.
  • Percutaneous angioplasty and stenting (PAS) is a potential treatment option.

Purpose of the Study:

  • To evaluate the safety, efficacy, and long-term outcomes of PAS for extracranial VA stenosis.
  • To identify challenges and potential solutions, such as stent selection and restenosis management.

Main Methods:

  • Comprehensive literature review of studies on PAS for extracranial VA stenosis.
  • Analysis of technical feasibility, complication rates, and long-term results.
  • Consideration of challenging cases, including severe vessel tortuosity and restenosis.

Main Results:

  • PAS appears safe and effective for improving symptoms and posterior circulation blood flow.
  • Stent placement can be challenging in tortuous vessels; coronary balloon-expandable stents may be preferred.
  • Restenosis rates show significant variability, suggesting drug-eluting stents as a potential solution.

Conclusions:

  • PAS is technically feasible for extracranial VA stenosis.
  • Current evidence from randomized trials is insufficient to establish endovascular management superiority over best medical management.

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