Related Experiment Video
Updated: May 18, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Endovascular treatment of extracranial vertebral artery stenosis
Burak Kocak1, Bora Korkmazer, Civan Islak
1Burak Kocak, Bora Korkmazer, Civan Islak, Naci Kocer, Osman Kizilkilic, Department of Radiology, Division of Neuroradiology, Cerrahpasa School of Medicine, Istanbul University, 34098 Istanbul, Turkey.
Insights
Percutaneous angioplasty and stenting for vertebral artery stenosis is a feasible treatment. However, more randomized trials are needed to prove its superiority over medical management.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Neurology
Background:
- Extracranial vertebral artery (VA) stenosis can cause posterior circulation symptoms.
- Percutaneous angioplasty and stenting (PAS) is a potential treatment option.
Purpose of the Study:
- To evaluate the safety, efficacy, and long-term outcomes of PAS for extracranial VA stenosis.
- To identify challenges and potential solutions, such as stent selection and restenosis management.
Main Methods:
- Comprehensive literature review of studies on PAS for extracranial VA stenosis.
- Analysis of technical feasibility, complication rates, and long-term results.
- Consideration of challenging cases, including severe vessel tortuosity and restenosis.
Main Results:
- PAS appears safe and effective for improving symptoms and posterior circulation blood flow.
- Stent placement can be challenging in tortuous vessels; coronary balloon-expandable stents may be preferred.
- Restenosis rates show significant variability, suggesting drug-eluting stents as a potential solution.
Conclusions:
- PAS is technically feasible for extracranial VA stenosis.
- Current evidence from randomized trials is insufficient to establish endovascular management superiority over best medical management.
Abstract:
Percutaneous angioplasty and stenting for the treatment of extracranial vertebral artery (VA) stenosis seems a safe, effective and useful technique for resolving symptoms and improving blood flow to the posterior circulation, with a low complication rate and good long-term results. In patients with severe tortuosity of the vessel, stent placement is a real challenge. The new coronary balloon-expandable stents may be preferred. A large variability of restenosis rates has been reported. Drug-eluting stents may be the solution. After a comprehensive review of the literature, it can be concluded that percutaneous angioplasty and stenting of extracranial VA stenosis is technically feasible, but there is insufficient evidence from randomized trials to demonstrate that endovascular management is superior to best medical management.
Related Concept Videos
Venous Thrombosis III: Interprofessional Care
Aneurysm III: Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care
Varicose Veins II: Diagnostic Studies and Interprofessional Care
