Related Experiment Video
Updated: May 18, 2026

Transcranial Direct Current Stimulation and Simultaneous Functional Magnetic Resonance Imaging
Published on: April 27, 2014
Cognitively Stimulating Activities: Effects on Cognition across Four Studies with up to 21 Years of Longitudinal Data
Meghan B Mitchell1, Cynthia R Cimino, Andreana Benitez
1Edith Nourse Rogers Memorial Veterans Hospital, Geriatric Research, Education and Clinical Center, Massachusetts General Hospital, Harvard Medical School, 200 Springs Road, Bedford, MA 01730, USA.
Abstract:
Engagement in cognitively stimulating activities has been considered to maintain or strengthen cognitive skills, thereby minimizing age-related cognitive decline. While the idea that there may be a modifiable behavior that could lower risk for cognitive decline is appealing and potentially empowering for older adults, research findings have not consistently supported the beneficial effects of engaging in cognitively stimulating tasks. Using observational studies of naturalistic cognitive activities, we report a series of mixed effects models that include baseline and change in cognitive activity predicting cognitive outcomes over up to 21 years in four longitudinal studies of aging. Consistent evidence was found for cross-sectional relationships between level of cognitive activity and cognitive test performance. Baseline activity at an earlier age did not, however, predict rate of decline later in life, thus not supporting the concept that engaging in cognitive activity at an earlier point in time increases one's ability to mitigate future age-related cognitive decline. In contrast, change in activity was associated with relative change in cognitive performance. Results therefore suggest that change in cognitive activity from one's previous level has at least a transitory association with cognitive performance measured at the same point in time.
Related Concept Videos
Longitudinal Research
Cognitive Development During Adulthood
Cognitivism
Previously dominated by behaviorism, which prioritized observable behaviors and largely ignored mental processes, psychology transformed in the 1950s. Cognitive psychologists argue that understanding how we think and process information is...
Longitudinal Studies
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
Long-term Potentiation
Hebbian LTP
LTP can occur when presynaptic neurons...
